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Scientific Evidence

In completed clinical trials, delivery of SAINT™ therapy for MDD has resulted in a significant reduction in depressive symptoms following the five-day treatment protocol.

MDD Efficacy
October 2021
Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial
American Journal of Psychiatry | Volume 179, Issue 2
View Authors Eleanor J. Cole, Ph.D., Angela L. Phillips, Ph.D., Brandon S. Bentzley, M.D., Ph.D., Katy H. Stimpson, B.S., Romina Nejad, M.S., Fahim Barmak, M.D., Clive Veerapal, B.S., Naushaba Khan, B.S., Kirsten Cherian, Ph.D., Emily Felber, M.S., Randi Brown, M.S., Elizabeth Choi, M.S., Sinead King, Ph.D., Heather Pankow, B.S., James H. Bishop, Ph.D., Azeezat Azeez, Ph.D., John Coetzee, Ph.D., Rachel Rapier, B.S., Nicole Odenwald, M.A., David Carreon, M.D., Jessica Hawkins, B.A., Maureen Chang, B.S., Jennifer Keller, Ph.D., Kristin Raj, M.D., Charles DeBattista, M.D., Booil Jo, Ph.D., Flint M. Espil, Ph.D., Alan F. Schatzberg, M.D., Keith D. Sudheimer, Ph.D., Nolan R. Williams, M.D
MDD Efficacy
April 2020
Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression
American Journal of Psychiatry | Volume 177, Issue 8
View Authors Eleanor J. Cole, Ph.D., Katy H. Stimpson, B.S., Brandon S. Bentzley, M.D., Ph.D., Merve Gulser, B.S., Kirsten Cherian, Ph.D., Claudia Tischler, B.S., Romina Nejad, M.S., Heather Pankow, B.S., Elizabeth Choi, B.S., Haley Aaron, B.S., Flint M. Espil, Ph.D., Jaspreet Pannu, B.S., Xiaoqian Xiao, Ph.D., Dalton Duvio, B.S., Hugh B. Solvason, M.D., Jessica Hawkins, B.A., Austin Guerra, B.A., Booil Jo, Ph.D., Kristin S. Raj, M.D., Angela L. Phillips, Ph.D., Fahim Barmak, M.D., James H. Bishop, Ph.D., John P. Coetzee, Ph.D., Charles DeBattista, M.D., Jennifer Keller, Ph.D., Alan F. Schatzberg, M.D., Keith D. Sudheimer, Ph.D., Nolan R. Williams, M.D.